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BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
Carmen Lai, Marcel J. T. Reinders, Laura J. van't ...
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
BMCBI
2006
86views more  BMCBI 2006»
13 years 8 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2007
179views more  BMCBI 2007»
13 years 8 months ago
Gene selection with multiple ordering criteria
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...
James J. Chen, Chen-An Tsai, ShengLi Tzeng, Chun-H...
BMCBI
2004
169views more  BMCBI 2004»
13 years 8 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...