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    BMCBI
    2010
    208views more  BMCBI 2010»
    Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
    13 years 7 months ago
    Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
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    Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
    Zafer Aydin, John I. Murray, Robert H. Waterston, ...
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    BMCBI
    2010
    135views more  BMCBI 2010»
    Detecting disease associated modules and prioritizing active genes based on high throughput data
    13 years 7 months ago
    Detecting disease associated modules and prioritizing active genes based on high throughput data
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    Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
    Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
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    BMCBI
    2007
    130views more  BMCBI 2007»
    Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
    13 years 7 months ago
    Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
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    Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
    Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
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    BMCBI
    2010
    123views more  BMCBI 2010»
    An improved classification of G-protein-coupled receptors using sequence-derived features
    13 years 7 months ago
    An improved classification of G-protein-coupled receptors using sequence-derived features
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    Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
    Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
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    BMCBI
    2008
    202views more  BMCBI 2008»
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
    13 years 7 months ago
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
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    Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
    Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
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