Large scale bioinformatics experiments are usually composed by a set of data flows generated by a chain of activities (programs or services) that may be modeled as scientific work...
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Message Sequence Charts (MSCs) are an appealing visual formalism mainly used in the early stages of system design to capture the system requirements. However, if we move towards a...
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...