Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
— Microarray technology offers a high throughput means to study expression networks and gene regulatory networks in cells. The intrinsic nature of high dimensionality and small s...
Yijuan Lu, Qi Tian, Maribel Sanchez, Jennifer L. N...
Background: There are several isolated tools for partial analysis of microarray expression data. To provide an integrative, easy-to-use and automated toolkit for the analysis of A...
Gabriela G. Loots, Patrick S. G. Chain, Shalini Ma...
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...