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BMCBI
2008
110views more  BMCBI 2008»
13 years 10 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BIOINFORMATICS
2006
92views more  BIOINFORMATICS 2006»
13 years 10 months ago
What should be expected from feature selection in small-sample settings
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Chao Sima, Edward R. Dougherty
BMCBI
2011
13 years 4 months ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou
BMCBI
2005
113views more  BMCBI 2005»
13 years 9 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
MAMMO
2010
Springer
13 years 8 months ago
Classifying Breast Masses in Volumetric Whole Breast Ultrasound Data: A 2.5-Dimensional Approach
The aim of this paper is to investigate a 2.5-dimensional approach in classifying masses as benign or malignant in volumetric anisotropic voxel whole breast ultrasound data. In thi...
Gobert N. Lee, Toshiaki Okada, Daisuke Fukuoka, Ch...