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BMCBI
2006
86views more  BMCBI 2006»
13 years 10 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
TMI
2002
90views more  TMI 2002»
13 years 9 months ago
Edge Displacement Field-Based Classification for Improved Detection of Polyps in CT Colonography
Colorectal cancer can easily be prevented provided that the precursors to tumors, small colonic polyps, are detected and removed. Currently, the only definitive examination of the ...
Burak Acar, Christopher F. Beaulieu, Salih Burak G...
BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
14 years 3 months ago
Joint Genomic and Metabolomic Analysis of Toxic Dose-Response Experiments
A methodology has been implemented for analyzing microarray and NMR spectral data obtained from the same set of toxic-exposure dose-response experiments. The NMR spectra additiona...
Gary L. Jahns, Nicholas J. DelRaso, Mark P. Westri...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 10 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li