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    BMCBI
    2007
    146views more  BMCBI 2007»
    Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
    13 years 7 months ago
    Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
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    Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
    Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
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    BMCBI
    2005
    201views more  BMCBI 2005»
    Principal component analysis for predicting transcription-factor binding motifs from array-derived data
    13 years 7 months ago
    Principal component analysis for predicting transcription-factor binding motifs from array-derived data
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    Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
    Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
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    TIT
    2010
    118views Education» more  TIT 2010»
    Joint sampling distribution between actual and estimated classification errors for linear discriminant analysis
    13 years 2 months ago
    Joint sampling distribution between actual and estimated classification errors for linear discriminant analysis
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    Error estimation must be used to find the accuracy of a designed classifier, an issue that is critical in biomarker discovery for disease diagnosis and prognosis in genomics and p...
    Amin Zollanvari, Ulisses Braga-Neto, Edward R. Dou...
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    BMCBI
    2010
    95views more  BMCBI 2010»
    An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
    13 years 7 months ago
    An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
    Download  www.biomedcentral.com
    Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
    Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
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    BMCBI
    2010
    155views more  BMCBI 2010»
    A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
    13 years 7 months ago
    A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
    Download  www.biomedcentral.com
    Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
    Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
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