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BMCBI
2007
94views more  BMCBI 2007»
15 years 4 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2007
149views more  BMCBI 2007»
15 years 4 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
IJCV
2008
192views more  IJCV 2008»
15 years 4 months ago
Learning to Locate Informative Features for Visual Identification
Object identification (OID) is specialized recognition where the category is known (e.g. cars) and the algorithm recognizes an object's exact identity (e.g. Bob's BMW). ...
Andras Ferencz, Erik G. Learned-Miller, Jitendra M...
BMCBI
2007
111views more  BMCBI 2007»
15 years 4 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
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