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» Web-Based Genomic Information Integration with Gene Ontology
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BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein tr
Background: Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where import...
Lawrence Hunter, Zhiyong Lu, James Firby, William ...
BMCBI
2011
13 years 3 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
BMCBI
2004
146views more  BMCBI 2004»
13 years 8 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker