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BMCBI
2008
13 years 8 months ago
2008
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
BMCBI
2008
13 years 8 months ago
2008
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
BMCBI
2008
13 years 8 months ago
2008
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
BMCBI
2008
13 years 8 months ago
2008
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
BMCBI
2008
13 years 8 months ago
2008
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...