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BMCBI
2010
154views more  BMCBI 2010»
13 years 5 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
BMCBI
2007
174views more  BMCBI 2007»
13 years 8 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
NAR
2006
156views more  NAR 2006»
13 years 7 months ago
VOMBAT: prediction of transcription factor binding sites using variable order Bayesian trees
Variable order Markov models and variable order Bayesian trees have been proposed for the recognition of transcription factor binding sites, and it could be demonstrated that they...
Jan Grau, Irad E. Ben-Gal, Stefan Posch, Ivo Gross...
SIAMSC
2010
142views more  SIAMSC 2010»
13 years 2 months ago
Hypergraph-Based Unsymmetric Nested Dissection Ordering for Sparse LU Factorization
In this paper we present HUND, a hypergraph-based unsymmetric nested dissection ordering algorithm for reducing the fill-in incurred during Gaussian elimination. HUND has several i...
Laura Grigori, Erik G. Boman, Simplice Donfack, Ti...