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BMCBI
2010
13 years 10 months ago
2010
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
BMCBI
2010
13 years 10 months ago
2010
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
BMCBI
2008
13 years 10 months ago
2008
Background: In cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: r...
BMCBI
2008
13 years 10 months ago
2008
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
BMCBI
2007
13 years 10 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...