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15 years 6 months ago
Genes, Themes, and Microarrays: Using Information Retrieval for Large-Scale Gene Analysis
The immensevolumeof data resulting from DNAmicroarray experiments, accompaniedby an increase in the numberof publications discussing gene-related discoveries, presents a majordata...
Hagit Shatkay, Stephen Edwards, W. John Wilbur, Ma...
PVLDB
2010
152views more  PVLDB 2010»
15 years 3 months ago
k-Nearest Neighbors in Uncertain Graphs
Complex networks, such as biological, social, and communication networks, often entail uncertainty, and thus, can be modeled as probabilistic graphs. Similar to the problem of sim...
Michalis Potamias, Francesco Bonchi, Aristides Gio...
BMCBI
2010
130views more  BMCBI 2010»
15 years 4 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
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BMCBI
2010
178views more  BMCBI 2010»
15 years 4 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
BMCBI
2010
97views more  BMCBI 2010»
15 years 4 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey