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BMCBI
2007
127views more  BMCBI 2007»
15 years 4 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BMCBI
2010
140views more  BMCBI 2010»
15 years 4 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng
BMCBI
2007
121views more  BMCBI 2007»
15 years 4 months ago
A procedure for identifying homologous alternative splicing events
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...
David Talavera, Adam Hospital, Modesto Orozco, Xav...
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BMCBI
2007
105views more  BMCBI 2007»
15 years 4 months ago
HoxPred: automated classification of Hox proteins using combinations of generalised profiles
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
Morgane Thomas-Chollier, Luc Leyns, Valérie...
BMCBI
2007
147views more  BMCBI 2007»
15 years 4 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...