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BMCBI
2006
127views more  BMCBI 2006»
15 years 4 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2006
130views more  BMCBI 2006»
15 years 4 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2006
178views more  BMCBI 2006»
15 years 4 months ago
MannDB - A microbial database of automated protein sequence analyses and evidence integration for protein characterization
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...
Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam...
BMCBI
2006
169views more  BMCBI 2006»
15 years 4 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
COMPLEXITY
2006
91views more  COMPLEXITY 2006»
15 years 4 months ago
The evolution of technology within a simple computer model
Technology--the collection of devices and methods available to human society--evolves by constructing new devices and methods from ones that previously exist, and in turn offering...
W. Brian Arthur, Wolfgang Polak