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BMCBI
2005
189views more  BMCBI 2005»
15 years 4 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
TCBB
2010
80views more  TCBB 2010»
15 years 2 months ago
On the Importance of Comprehensible Classification Models for Protein Function Prediction
—The literature on protein function prediction is currently dominated by works aimed at maximizing predictive accuracy, ignoring the important issues of validation and interpreta...
Alex Alves Freitas, Daniela Wieser, Rolf Apweiler
FP
1991
95views Formal Methods» more  FP 1991»
15 years 8 months ago
Making Functionality More General
The notion of functionality is not cast in stone, but depends upon what we have as types in our language. With partial equivalence relations (pers) as types we show that the funct...
Graham Hutton, Ed Voermans
RECOMB
2006
Springer
16 years 4 months ago
Identification and Evaluation of Functional Modules in Gene Co-expression Networks
Abstract. Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. In this paper, we introduce a simple method to construct ge...
Jianhua Ruan, Weixiong Zhang
RECOMB
2005
Springer
16 years 4 months ago
A Hidden Markov Model Based Scoring Function for Mass Spectrometry Database Search
An accurate scoring function for database search is crucial for peptide identification using tandem mass spectrometry. Although many mathematical models have been proposed to scor...
Yunhu Wan, Ting Chen