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BMCBI
2010
134views more  BMCBI 2010»
13 years 7 months ago
ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...
John C. Dittmar, Robert J. D. Reid, Rodney Rothste...
BMCBI
2010
112views more  BMCBI 2010»
13 years 7 months ago
A parameter-adaptive dynamic programming approach for inferring cophylogenies
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
Daniel Merkle, Martin Middendorf, Nicolas Wieseke
BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer