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185
Voted
BMCBI
2011
14 years 7 months ago
2011
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
168
Voted
BMCBI
2011
14 years 7 months ago
2011
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
166
Voted
BMCBI
2011
14 years 7 months ago
2011
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
154
Voted
BMCBI
2011
14 years 7 months ago
2011
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
147
Voted
BMCBI
2011
14 years 7 months ago
2011
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...