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BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
TiGER: A database for tissue-specific gene expression and regulation
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...
BMCBI
2008
148views more  BMCBI 2008»
13 years 7 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
PASSIM - an open source software system for managing information in biomedical studies
Background: One of the crucial aspects of day-to-day laboratory information management is collection, storage and retrieval of information about research subjects and biomedical s...
Juris Viksna, Edgars Celms, Martins Opmanis, Karli...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
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