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BMCBI
2011
12 years 11 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BMCBI
2011
12 years 11 months ago
PI: An open-source software package for validation of the SEQUEST result and visualization of mass spectrum
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...
Yantao Qiao, Hong Zhang, Dongbo Bu, Shiwei Sun
BMCBI
2011
12 years 11 months ago
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and STRUCTU
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...
Tulaya Limpiti, Apichart Intarapanich, Anunchai As...
BMCBI
2011
12 years 11 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
CGF
2011
12 years 11 months ago
Estimating Color and Texture Parameters for Vector Graphics
Diffusion curves are a powerful vector graphic representation that stores an image as a set of 2D Bezier curves with colors defined on either side. These colors are diffused over...
Stefan Jeschke, David Cline, Peter Wonka
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