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BMCBI
2010
13 years 7 months ago
2010
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
BMCBI
2007
13 years 7 months ago
2007
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
BMCBI
2008
13 years 7 months ago
2008
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
BMCBI
2008
13 years 7 months ago
2008
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
BMCBI
2008
13 years 7 months ago
2008
Background: It has been previously shown that palindromic sequences are frequently observed in proteins. However, our knowledge about their evolutionary origin and their possible ...