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BMCBI
2010
103views more  BMCBI 2010»
13 years 8 months ago
Detecting internally symmetric protein structures
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Changhoon Kim, Jodi Basner, Byungkook Lee
BMCBI
2010
117views more  BMCBI 2010»
13 years 8 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2007
128views more  BMCBI 2007»
13 years 8 months ago
A Bayesian nonparametric method for prediction in EST analysis
Background: Expressed sequence tags (ESTs) analyses are a fundamental tool for gene identification in organisms. Given a preliminary EST sample from a certain library, several sta...
Antonio Lijoi, Ramsés H. Mena, Igor Prü...
BMCBI
2008
173views more  BMCBI 2008»
13 years 8 months ago
Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
Stephen W. Tanner, Pankaj Agarwal
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...