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BMCBI
2011
13 years 9 days ago
Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure
Background: Protein secondary structure prediction provides insight into protein function and is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic ...
Zafer Aydin, Ajit Singh, Jeff Bilmes, William Staf...
CAV
2010
Springer
251views Hardware» more  CAV 2010»
14 years 19 days ago
Automated Assume-Guarantee Reasoning through Implicit Learning
Abstract. We propose a purely implicit solution to the contextual assumption generation problem in assume-guarantee reasoning. Instead of improving the L∗ algorithm — a learnin...
Yu-Fang Chen, Edmund M. Clarke, Azadeh Farzan, Min...
BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2007
116views more  BMCBI 2007»
13 years 8 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...