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ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 8 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
ALGORITHMICA
2005
149views more  ALGORITHMICA 2005»
13 years 8 months ago
Approximating Maximum Weight Cycle Covers in Directed Graphs with Weights Zero and One
A cycle cover of a graph is a spanning subgraph each node of which is part of exactly one simple cycle. A k-cycle cover is a cycle cover where each cycle has length at least k. Gi...
Markus Bläser, Bodo Manthey
ALGORITHMICA
2008
95views more  ALGORITHMICA 2008»
13 years 8 months ago
Optimality in External Memory Hashing
Hash tables on external memory are commonly used for indexing in database management systems. In this paper we present an algorithm that, in an asymptotic sense, achieves the best...
Morten Skaarup Jensen, Rasmus Pagh
ALGORITHMICA
2007
114views more  ALGORITHMICA 2007»
13 years 8 months ago
The Consecutive Ones Submatrix Problem for Sparse Matrices
A 0-1 matrix has the Consecutive Ones Property (C1P) if there is a permutation of its columns that leaves the 1’s consecutive in each row. The Consecutive Ones Submatrix (C1S) p...
Jinsong Tan, Louxin Zhang
ALGORITHMICA
2007
165views more  ALGORITHMICA 2007»
13 years 8 months ago
Motorcycle Graphs and Straight Skeletons
We present a new algorithm to compute motorcycle graphs. It runs in O(n √ n log n) time when n is the number of motorcycles. We give a new characterization of the straight skele...
Siu-Wing Cheng, Antoine Vigneron