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BIOCOMP
2007
13 years 11 months ago
Aldose Reductase and Nitric Oxide Synthase Role in Diabetic Retinopathy: A Bioinformatics Study
- Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus. We investigated the role of several proteins that are likely to be involved in the d...
Hanuman Thota, Nageswara rao Kunjam, Suresh Babu C...
BIOCOMP
2007
13 years 11 months ago
Learning Node Replacement Graph Grammars in Metabolic Pathways
— This paper describes graph-based relational, unsupervised learning algorithm to infer node replacement graph grammar and its application to metabolic pathways. We search for fr...
Jacek P. Kukluk, Chang Hun You, Lawrence B. Holder...
BIOCOMP
2006
13 years 11 months ago
Melting Free Energies of DNA Duplexes with oxidized Base Residues and Abasic sites: A Molecular Dynamics Characterization
: Ionizing radiation alters DNA strands and mainly creates multiply damaged sites (MDS), e.g. two or more damaged sites within one or two turns of the DNA (10 to 20 base pairs). Th...
Latifa Douali, Matt Ernst, John Miller, Michel Dup...
BIOCOMP
2006
13 years 11 months ago
The Multi-Node Topological Overlap Measure For Gene Neighborhood Analysis
Defining the neighborhood of an initial set of nodes is an important task in network analysis. For example, we show that the neighborhood of an initial set of brain cancer related ...
Ai Li, Steve Horvath
BIOCOMP
2006
13 years 11 months ago
Membrane Remodeling and Diffusion of Cytochrome C from a Geometrically Idealized Mitochondrial Crista
In healthy eukaryotic cells, mitochondria have an outer membrane that surrounds a complex inner membrane structure [7,8]. Cytochrome c is found in the space between the two membra...
John Manor, Peter Salamon, James Nulton, Joseph Ma...