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BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
BMCBI
2006
101views more  BMCBI 2006»
13 years 8 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
BMCBI
2006
135views more  BMCBI 2006»
13 years 8 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
374views more  BMCBI 2006»
13 years 8 months ago
AMDA: an R package for the automated microarray data analysis
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
Mattia Pelizzola, Norman Pavelka, Maria Foti, Paol...