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BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 10 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
13 years 10 months ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...
TC
2010
13 years 8 months ago
Network-on-Chip Hardware Accelerators for Biological Sequence Alignment
—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Souradip Sarkar, Gaurav Ramesh Kulkarni, Partha Pr...
BIBE
2010
IEEE
137views Bioinformatics» more  BIBE 2010»
13 years 11 months ago
Comparison of Gene Prediction Programs for Metagenomic Data
This manuscript presents the most rigorous benchmarking of gene annotation algorithms for metagenomic datasets to date. We compare three different programs: GeneMark, MetaGeneAnnot...
Non Yok, Gail Rosen
WABI
2010
Springer
124views Bioinformatics» more  WABI 2010»
13 years 8 months ago
Improved Orientations of Physical Networks
Abstract. The orientation of physical networks is a prime task in deciphering the signaling-regulatory circuitry of the cell. One manifestation of this computational task is as a m...
Iftah Gamzu, Danny Segev, Roded Sharan