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BMCBI
2005
73views more  BMCBI 2005»
13 years 11 months ago
Exploring the boundaries: gene and protein identification in biomedical text
We present a maximum-entropy based system incorporating a diverse set of features for identifying genes and proteins in biomedical s. This system was entered in the BioCreative co...
Jenny Rose Finkel, Shipra Dingare, Christopher D. ...
BMCBI
2005
120views more  BMCBI 2005»
13 years 11 months ago
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools
Background: This paper describes a microarray study including data quality control, data analysis and the analysis of the mechanism of toxicity (MOT) induced by 1-methyl-4-phenylp...
Zengjun Xu, Tucker A. Patterson, Jonathan D. Wren,...
BMCBI
2005
140views more  BMCBI 2005»
13 years 11 months ago
JACOP: A simple and robust method for the automated classification of protein sequences with modular architecture
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...
Peter Sperisen, Marco Pagni
BMCBI
2005
118views more  BMCBI 2005»
13 years 11 months ago
Feature selection and classification for microarray data analysis: Evolutionary methods for identifying predictive genes
Background: In the clinical context, samples assayed by microarray are often classified by cell line or tumour type and it is of interest to discover a set of genes that can be us...
Thanyaluk Jirapech-Umpai, J. Stuart Aitken
BMCBI
2005
92views more  BMCBI 2005»
13 years 11 months ago
A decoy set for the thermostable subdomain from chicken villin headpiece, comparison of different free energy estimators
Background: Estimators of free energies are routinely used to judge the quality of protein structural models. As these estimators still present inaccuracies, they are frequently e...
Federico Fogolari, Silvio C. E. Tosatto, Giorgio C...