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BMCBI
2005
97views more  BMCBI 2005»
13 years 9 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2005
94views more  BMCBI 2005»
13 years 9 months ago
Reproducible Clusters from Microarray Research: Whither?
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...
Nikhil R. Garge, Grier P. Page, Alan P. Sprague, B...
BMCBI
2005
134views more  BMCBI 2005»
13 years 9 months ago
Systematic feature evaluation for gene name recognition
In task 1A of the BioCreAtIvE evaluation, systems had to be devised that recognize words and phrases forming gene or protein names in natural language sentences. We approach this ...
Jörg Hakenberg, Steffen Bickel, Conrad Plake,...
BMCBI
2005
114views more  BMCBI 2005»
13 years 9 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
BMCBI
2005
148views more  BMCBI 2005»
13 years 9 months ago
NemaFootPrinter: a web based software for the identification of conserved non-coding genome sequence regions between C. elegans
Background: NemaFootPrinter (Nematode Transcription Factor Scan Through Philogenetic Footprinting) is a web-based software for interactive identification of conserved, non-exonic ...
Davide Rambaldi, Alessandro Guffanti, Paolo Morand...