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BMCBI
2008
13 years 8 months ago
2008
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
BMCBI
2008
13 years 8 months ago
2008
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
BMCBI
2008
13 years 8 months ago
2008
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
BMCBI
2008
13 years 8 months ago
2008
Background: Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as U...
BMCBI
2008
13 years 8 months ago
2008
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...