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BMCBI
2008
170views more  BMCBI 2008»
13 years 8 months ago
Implementing EM and Viterbi algorithms for Hidden Markov Model in linear memory
Background: The Baum-Welch learning procedure for Hidden Markov Models (HMMs) provides a powerful tool for tailoring HMM topologies to data for use in knowledge discovery and clus...
Alexander G. Churbanov, Stephen Winters-Hilt
BMCBI
2008
76views more  BMCBI 2008»
13 years 8 months ago
Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
Metabotropic glutamate receptors (mGluRs) are G protein coupled receptors that play important roles in synaptic plasticity and other neuro-physiological and pathological processes...
Naveena Yanamala, Kalyan C. Tirupula, Judith Klein...
BMCBI
2008
125views more  BMCBI 2008»
13 years 8 months ago
Competition between protein aggregation and protein complex formation
ent> <title> <p>Highlights from the Fourth International Society for Computational Biology (ISCB) Student Council Symposium</p> </title> <editor>Lu...
Sebastian Pechmann, Emmanuel D. Levy, Gian G. Tart...
BMCBI
2008
104views more  BMCBI 2008»
13 years 8 months ago
ExonMiner: Web service for analysis of GeneChip Exon array data
Background: Some splicing isoform-specific transcriptional regulations are related to disease. Therefore, detection of disease specific splice variations is the first step for fin...
Kazuyuki Numata, Ryo Yoshida, Masao Nagasaki, Ayum...
BMCBI
2008
88views more  BMCBI 2008»
13 years 8 months ago
Data capture in bioinformatics: requirements and experiences with Pedro
Background: The systematic capture of appropriately annotated experimental data is a prerequisite for most bioinformatics analyses. Data capture is required not only for submissio...
Daniel Jameson, Kevin L. Garwood, Christopher Garw...