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BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images
Background: A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dyn...
Yoshitaka Kimori, Norio Baba, Nobuhiro Morone
BMCBI
2010
177views more  BMCBI 2010»
15 years 6 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2010
100views more  BMCBI 2010»
15 years 3 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
BMCBI
2010
143views more  BMCBI 2010»
15 years 3 months ago
A genome alignment algorithm based on compression
Background: Traditional genome alignment methods consider sequence alignment as a variation of the string edit distance problem, and perform alignment by matching characters of th...
Minh Duc Cao, Trevor I. Dix, Lloyd Allison