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181
Voted
BMCBI
2011
14 years 8 months ago
2011
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
180
Voted
BMCBI
2011
14 years 8 months ago
2011
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
175
Voted
BMCBI
2011
14 years 8 months ago
2011
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
194
Voted
BMCBI
2011
14 years 8 months ago
2011
Background: Constraint-based approaches facilitate the prediction of cellular metabolic capabilities, based, in turn on predictions of the repertoire of enzymes encoded in the gen...
158
Voted
BMCBI
2011
14 years 8 months ago
2011
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...