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BMCBI
2010
162views more  BMCBI 2010»
13 years 9 months ago
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Che...
BMCBI
2010
177views more  BMCBI 2010»
13 years 9 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
BMCBI
2007
135views more  BMCBI 2007»
13 years 9 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2007
159views more  BMCBI 2007»
13 years 9 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
CC
2008
Springer
133views System Software» more  CC 2008»
13 years 9 months ago
Hardness Amplification via Space-Efficient Direct Products
We prove a version of the derandomized Direct Product lemma for deterministic space-bounded algorithms. Suppose a Boolean function g : {0, 1}n {0, 1} cannot be computed on more th...
Venkatesan Guruswami, Valentine Kabanets
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