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BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
Erik Arner, Martti T. Tammi, Anh-Nhi Tran, Ellen K...
BMCBI
2006
87views more  BMCBI 2006»
13 years 7 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
IJCAI
2003
13 years 9 months ago
Decidability of SHIQ with Complex Role Inclusion Axioms
Motivated by medical terminology applications, we investigate the decidability of the well known expressive DL, SHIQ, extended with role inclusion axioms (RIAs) of the form R ◦ ...
Ian Horrocks, Ulrike Sattler
BMCBI
2007
88views more  BMCBI 2007»
13 years 8 months ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...