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BMCBI
2010
167views more  BMCBI 2010»
13 years 9 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
CORR
2010
Springer
149views Education» more  CORR 2010»
13 years 9 months ago
Group Testing with Probabilistic Tests: Theory, Design and Application
Identification of defective members of large populations has been widely studied in the statistics community under the name of group testing. It involves grouping subsets of items...
Mahdi Cheraghchi, Ali Hormati, Amin Karbasi, Marti...
BMCBI
2010
98views more  BMCBI 2010»
13 years 9 months ago
miRMaid: a unified programming interface for microRNA data resources
Background: MicroRNAs (miRNAs) are endogenous small RNAs that play a key role in post-transcriptional regulation of gene expression in animals and plants. The number of known miRN...
Anders Jacobsen, Anders Krogh, Sakari Kauppinen, M...
BMCBI
2010
137views more  BMCBI 2010»
13 years 9 months ago
TassDB2 - A comprehensive database of subtle alternative splicing events
Background: Subtle alternative splicing events involving tandem splice sites separated by a short (2-12 nucleotides) distance are frequent and evolutionarily widespread in eukaryo...
Rileen Sinha, Thorsten Lenser, Niels Jahn, Ulrike ...
BMCBI
2010
96views more  BMCBI 2010»
13 years 9 months ago
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
Background: Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standar...
Lihua J. Zhu, Claude Gazin, Nathan D. Lawson, Herv...