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    BIOINFORMATICS
    2006
    92views more  BIOINFORMATICS 2006»
    What should be expected from feature selection in small-sample settings
    13 years 8 months ago
    What should be expected from feature selection in small-sample settings
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    Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
    Chao Sima, Edward R. Dougherty
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    BMCBI
    2006
    106views more  BMCBI 2006»
    Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
    13 years 8 months ago
    Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
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    Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
    Henrik Bengtsson, Ola Hössjer
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    BMCBI
    2006
    144views more  BMCBI 2006»
    Development and implementation of an algorithm for detection of protein complexes in large interaction networks
    13 years 8 months ago
    Development and implementation of an algorithm for detection of protein complexes in large interaction networks
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    Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
    Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
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    BMCBI
    2006
    103views more  BMCBI 2006»
    Correction of scaling mismatches in oligonucleotide microarray data
    13 years 8 months ago
    Correction of scaling mismatches in oligonucleotide microarray data
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    Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
    Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
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    BMCBI
    2006
    170views more  BMCBI 2006»
    Biclustering of gene expression data by non-smooth non-negative matrix factorization
    13 years 8 months ago
    Biclustering of gene expression data by non-smooth non-negative matrix factorization
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    Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
    Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
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