Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...