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BMCBI
2005
94views more  BMCBI 2005»
13 years 10 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
BMCBI
2005
212views more  BMCBI 2005»
13 years 10 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
BMCBI
2005
127views more  BMCBI 2005»
13 years 10 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2005
97views more  BMCBI 2005»
13 years 10 months ago
The yeast kinome displays scale free topology with functional hub clusters
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
Robin E. C. Lee, Lynn A. Megeney
BMCBI
2005
190views more  BMCBI 2005»
13 years 10 months ago
An Entropy-based gene selection method for cancer classification using microarray data
Background: Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of n...
Xiaoxing Liu, Arun Krishnan, Adrian Mondry