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BMCBI
2005
13 years 8 months ago
2005
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
BMCBI
2005
13 years 8 months ago
2005
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
BMCBI
2005
13 years 8 months ago
2005
Background: Complete sequencing of bacterial genomes has become a common technique of present day microbiology. Thereafter, data mining in the complete sequence is an essential st...
BMCBI
2005
13 years 8 months ago
2005
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
BMCBI
2005
13 years 8 months ago
2005
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...