In 1957 Crick hypothesized that the genetic code was a comma free code. This property would imply the existence of a universal coding frame and make the set of coding sequences a ...
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties, with potential implications ...
Alexander G. Churbanov, Carl Baribault, Stephen Wi...