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BMCBI
2008
103views more  BMCBI 2008»
13 years 9 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone
BMCBI
2008
86views more  BMCBI 2008»
13 years 9 months ago
Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets
Background: In plant mitochondria, the post-transcriptional RNA editing process converts C to U at a number of specific sites of the mRNA sequence and usually restores phylogeneti...
Ernesto Picardi, Carla Quagliariello
BMCBI
2008
102views more  BMCBI 2008»
13 years 9 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
NAR
2008
91views more  NAR 2008»
13 years 9 months ago
GenBank
GenBank (R) is a comprehensive sequence database that contains publicly available DNA sequences for more than 119 000 different organisms, obtained primarily through the submissio...
Dennis A. Benson, Ilene Karsch-Mizrachi, David J. ...
ISMB
2008
14 years 33 min ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...