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AINA
2006
IEEE
14 years 1 months ago
Partitioned optimization algorithms for multiple sequence alignment
Multiple sequence alignment is an important and difficult problem in molecular biology and bioinformatics. In this paper, we propose a partitioning approach that significantly impr...
Yixin Chen, Yi Pan, Juan Chen, Wei Liu, Ling Chen
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Ma...
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2004
189views more  BMCBI 2004»
13 years 7 months ago
B.E.A.R. GeneInfo: A tool for identifying gene-related biomedical publications through user modifiable queries
Background: Once specific genes are identified through high throughput genomics technologies there is a need to sort the final gene list to a manageable size for validation studie...
Guohui Zhou, Xinyu Wen, Hang Liu, Michael J. Schli...
BMCBI
2010
164views more  BMCBI 2010»
13 years 4 months ago
Merged consensus clustering to assess and improve class discovery with microarray data
Background: One of the most commonly performed tasks when analysing high throughput gene expression data is to use clustering methods to classify the data into groups. There are a...
T. Ian Simpson, J. Douglas Armstrong, Andrew P. Ja...