B.E.A.R. GeneInfo: A tool for identifying gene-related biomedical publications through user modifiable queries

Background: Once specific genes are identified through high throughput genomics technologies there is a need to sort the final gene list to a manageable size for validation studies. The triaging and sorting of genes often relies on the use of supplemental information related to gene structure, metabolic pathways, and chromosomal location. Yet in disease states where the genes may not have identifiable structural elements, poorly defined metabolic pathways, or limited chromosomal data, flexible systems for obtaining additional data are necessary. In these situations having a tool for searching the biomedical literature using the list of identified genes while simultaneously defining additional search terms would be useful. Results: We have built a tool, BEAR GeneInfo, that allows flexible searches based on the investigators knowledge of the biological process, thus allowing for data mining that is specific to the scientist's strengths and interests. This tool allows a user to uplo...

• Type: Journal
• Year: 2004
• Where: BMCBI
• Authors: Guohui Zhou, Xinyu Wen, Hang Liu, Michael J. Schlicht, Martin J. Hessner, Peter J. Tonellato, Milton W. Datta
• Keywords: BMCBI 2004, Gene Names, Metabolic Pathways, Tool