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BMCBI
2010
13 years 9 months ago
2010
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
BMCBI
2010
13 years 9 months ago
2010
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
BMCBI
2010
13 years 9 months ago
2010
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
BMCBI
2010
13 years 9 months ago
2010
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
BMCBI
2010
13 years 9 months ago
2010
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...