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JCB
2007
130views more  JCB 2007»
13 years 7 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
JSAC
2007
128views more  JSAC 2007»
13 years 7 months ago
Understanding the Power of Pull-Based Streaming Protocol: Can We Do Better?
— Most of the real deployed peer-to-peer streaming systems adopt pull-based streaming protocol. In this paper, we demonstrate that, besides simplicity and robustness, with proper...
Meng Zhang, Qian Zhang, Lifeng Sun, Shiqiang Yang
LMCS
2007
132views more  LMCS 2007»
13 years 7 months ago
The Complexity of Model Checking Higher-Order Fixpoint Logic
Higher-Order Fixpoint Logic (HFL) is a hybrid of the simply typed λ-calculus and the modal µ-calculus. This makes it a highly expressive temporal logic that is capable of express...
Roland Axelsson, Martin Lange, Rafal Somla
BIOINFORMATICS
2004
119views more  BIOINFORMATICS 2004»
13 years 7 months ago
Analysis of variance components in gene expression data
Motivation: A microarray experiment is a multi-step process, and each step is a potential source of variation. There are two major sources of variation: biological variation and t...
James J. Chen, Robert R. Delongchamp, Chen-An Tsai...
BMCBI
2004
323views more  BMCBI 2004»
13 years 7 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...