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BMCBI
2006
163views more  BMCBI 2006»
13 years 6 months ago
Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological featur
Background: Ensemble attribute profile clustering is a novel, text-based strategy for analyzing a userdefined list of genes and/or proteins. The strategy exploits annotation data ...
J. R. Semeiks, A. Rizki, Mina J. Bissell, I. Saira...
BMCBI
2006
108views more  BMCBI 2006»
13 years 6 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
157views more  BMCBI 2006»
13 years 6 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik
BMCBI
2007
123views more  BMCBI 2007»
13 years 6 months ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
BMCBI
2007
148views more  BMCBI 2007»
13 years 6 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole