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134
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BMCBI
2006
15 years 4 months ago
2006
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
154
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BMCBI
2006
15 years 4 months ago
2006
Background: The genomic information of a species allows for the genome-scale reconstruction of its metabolic capacity. Such a metabolic reconstruction gives support to metabolic e...
125
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BMCBI
2006
15 years 4 months ago
2006
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
126
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CCE
2006
15 years 4 months ago
2006
Principal differential analysis (PDA) is an alternative parameter estimation technique for differential equation models in which basis functions (e.g., B-splines) are fitted to dy...
141
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CCE
2006
15 years 4 months ago
2006
This paper describes the development of a real-time monitoring system for a batch process operated by Aroma and Fine Chemicals Limited. The process shares many similarities with o...