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106
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BMCBI
2006
15 years 3 months ago
2006
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
116
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BMCBI
2006
15 years 3 months ago
2006
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
127
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BMCBI
2006
15 years 3 months ago
2006
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
141
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BMCBI
2006
15 years 3 months ago
2006
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
153
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BMCBI
2006
15 years 3 months ago
2006
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...