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BMCBI
2008
157views more  BMCBI 2008»
15 years 3 months ago
Dimension reduction with redundant gene elimination for tumor classification
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
Xue-Qiang Zeng, Guo-Zheng Li, Jack Y. Yang, Mary Q...
BMCBI
2008
122views more  BMCBI 2008»
15 years 3 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
131
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BMCBI
2008
120views more  BMCBI 2008»
15 years 3 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
112
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BMCBI
2008
79views more  BMCBI 2008»
15 years 3 months ago
In silico docking of urokinase plasminogen activator and integrins
Background: Urokinase, its receptor and the integrins are functionally associated and involved in regulation of cell signaling, migration, adhesion and proliferation. No structura...
Bernard Degryse, Juan Fernández-Recio, Vale...
177
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BMCBI
2008
134views more  BMCBI 2008»
15 years 3 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
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