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BMCBI
2010
129views more  BMCBI 2010»
15 years 4 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2010
233views more  BMCBI 2010»
15 years 4 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
BMCBI
2010
218views more  BMCBI 2010»
15 years 4 months ago
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Background: Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...
Michael Scharfe, Rainer Pielot, Falk Schreiber
144
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BMCBI
2010
84views more  BMCBI 2010»
15 years 4 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
132
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BMCBI
2010
103views more  BMCBI 2010»
15 years 4 months ago
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
Inkyung Jung, Akihisa Matsuyama, Minoru Yoshida, D...
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